MRI评估深部脑刺激可引起脑静脉血流改变

深部脑刺激在治疗运动障碍方面应用越来越广泛,但其对大脑血管系统的影响尚不明了。虽然已有研究者应用PET研究深部脑刺激后大脑细胞代谢的情况,但深部脑刺激后脑血管系统的变化尚未见研究。韩国蔚山大学医学院Haeundae Paik医院Byeong Sam Choi博士所在团队,应用双倍剂量钆增强脑MRI评估深部脑刺激治疗患者的脑血管系统,发现直窦、上矢状窦、丘脑支脑内静脉、前尾状核静脉尺寸均有所减小。

SICENCE新闻发布 作者： Byeong Sam Choi 稿号：N201305009

MRI评估深部脑刺激可引起脑静脉血流改变

深部脑刺激在治疗运动障碍方面应用越来越广泛，但其对大脑血管系统的影响尚不明了。虽然已有研究者应用PET研究深部脑刺激后大脑细胞代谢的情况，但深部脑刺激后脑血管系统的变化尚未见研究。韩国蔚山大学医学院Haeundae Paik医院Byeong Sam Choi博士所在团队，应用双倍剂量钆增强脑MRI评估深部脑刺激治疗患者的脑血管系统，发现直窦、上矢状窦、丘脑支脑内静脉、前尾状核静脉尺寸均有所减小。认为双侧丘脑底核深部脑刺激可影响脑静脉血流。研究成果发表于《中国神经再生研究（英文版）》杂志2014年2月第3期。

Article: " Vascular changes caused by deep brain stimulation using double-dose gadolinium-enhanced brain MRI" by Byeong Sam Choi1, Yong Hwan Kim2, Sang Ryong Jeon (1 Department of Neurological Surgery, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea; 2 Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, IN, USA; 3 Department of Neurological Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea)

Choi BS, Kim YH, Jeon SR. Vascular changes caused by deep brain stimulation using double-dose gadolinium-enhanced brain MRI. Neural Regen Res. 2014;9(3):276-279.

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Vascular changes caused by deep brain stimulation using brain MRI

Deep brain stimulation has been widely used to treat patients with movement disorders and increasing attention has been paid to its use in the treatment of neurological and psychiatric disorders. However, the influence of subthalamic nucleus or pallidal deep brain stimulation on cerebral vasculature is poorly understood. Even though the metabolic changes caused by deep brain stimulation are being studied using positron emission tomography, the structural changes in cerebral areas like the intracerebral vasculature have not yet been evaluated. Dr. Byeong Sam Choi and colleagues from Haeundae Paik Hospital, Inje University College of Medicine in Korea performed a retrospective analysis on vasculature changes caused by deep brain stimulation in patients with medically intractable idiopathic Parkinson’s disease using double-dose gadolinium-enhanced brain MRI. The dimensions of straight sinus, superior sagittal sinus, ipsilateral internal cerebral vein in the thalamic branch and ipsilateral anterior caudate vein were reduced. These findings, published in the Neural Regeneration Research (Vol. 9, No. 3, 2014), demonstrate that bilateral deep brain stimulation of the subthalamic nuclei affects cerebral venous blood flow.

深部脑刺激在治疗运动障碍方面应用越来越广泛,但其对大脑血管系统的影响尚不明了。虽然已有研究者应用PET研究深部脑刺激后大脑细胞代谢的情况,但深部脑刺激后脑血管系统的变化尚未见研究。韩国蔚山大学医学院Haeundae Paik医院Byeong Sam Choi博士所在团队,应用双倍剂量钆增强脑MRI评估深部脑刺激治疗患者的脑血管系统,发现直窦、上矢状窦、丘脑支脑内静脉、前尾状核静脉尺寸均有所减小。

SICENCE新闻发布 作者： Byeong Sam Choi 稿号：N201305009

Article: " Vascular changes caused by deep brain stimulation using double-dose gadolinium-enhanced brain MRI" by Byeong Sam Choi1, Yong Hwan Kim2, Sang Ryong Jeon (1 Department of Neurological Surgery, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea; 2 Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, IN, USA; 3 Department of Neurological Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea)

Choi BS, Kim YH, Jeon SR. Vascular changes caused by deep brain stimulation using double-dose gadolinium-enhanced brain MRI. Neural Regen Res. 2014;9(3):276-279.