改良神经导管与粘合剂吻合技术修复损伤坐骨神经

以往研究应用粘合剂吻合修复神经时,均直接将粘合剂滴到神经断端,该方法不利于神经断端固定,且粘合剂易侵入断端。而所采用的圆柱形神经导管亦不方便操作,不能将粘合剂吻合技术与其完美结合,影响神经修复效果。中国解放军总医院梁向党所在课题组改良了传统神经导管的圆柱外形,使其更方便的应用在粘合剂吻合技术中,同时对最适导管直径进行优化设计。结果证实,应用改进的神经导管与粘合剂吻合技术修复周围神经有效可行。

改良神经导管与粘合剂吻合技术修复损伤坐骨神经

以往研究应用粘合剂吻合修复神经时，均直接将粘合剂滴到神经断端，该方法不利于神经断端固定，且粘合剂易侵入断端。而所采用的圆柱形神经导管亦不方便操作，不能将粘合剂吻合技术与其完美结合，影响神经修复效果。中国解放军总医院梁向党所在课题组改良了传统神经导管的圆柱外形，使其更方便的应用在粘合剂吻合技术中，同时对最适导管直径进行优化设计。结果证实，应用改进的神经导管与粘合剂吻合技术修复周围神经有效可行，大幅缩短操作时间，达到与缝合法相同的修复效果。文章发表在《中国神经再生研究（英文版）》杂志2014年3月第6期。

透射电镜下观察可见，应用粘合剂吻合技术及改进的神经导管修复的坐骨神经现为排列整齐（×1 000） Article: " Sciatic nerve repair using adhesive bonding and a modifed conduit," by Xiangdang Liang1, Hongfei Cai 1, Yongyu Hao2, Geng Sun3, Yaoyao Song1, Wen Chen1 (1 Department of Orthopedics, General Hospital of Chinese PLA, Beijing, China; 2 Wei Zikeng Clinic of General Armament Department of Chinese PLA, Beijing, China; 3 Department of Orthopedics, 252 Hospital of Chinese PLA, Hebei Province, China)

Liang XD, Cai HF, Hao YY, Sun G, Song YY, Chen W. Sciatic nerve repair using adhesive bonding and a modified conduit. Neural Regen Res.

2014;9(6):594-601.

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Sciatic nerve repair using adhesive bonding and a modified conduit

When repairing nerves with adhesives, most researchers place glue directly on the nerve stumps, but this method does not fix the nerve ends well and allows glue to easily invade the nerve ends. Ordinarily, nerve conduits are cylindrical. However, it is difficult to insert the nerve ends into the conduit because the nerve is soft and there is frictional resistance. Xiangdang Liang and co-workers from the General Hospital of Chinese PLA designed a special conduit for the adhesive technique and defined the best parameters for its use through in vitro testing, and then repaired nerves with cyanoacrylate and the

以往研究应用粘合剂吻合修复神经时,均直接将粘合剂滴到神经断端,该方法不利于神经断端固定,且粘合剂易侵入断端。而所采用的圆柱形神经导管亦不方便操作,不能将粘合剂吻合技术与其完美结合,影响神经修复效果。中国解放军总医院梁向党所在课题组改良了传统神经导管的圆柱外形,使其更方便的应用在粘合剂吻合技术中,同时对最适导管直径进行优化设计。结果证实,应用改进的神经导管与粘合剂吻合技术修复周围神经有效可行。

modified conduit in an in vivo rat model. This adhesive method for repairing nerves using a modified conduit is feasible and effective, and reduces the operation time while providing an equivalent repair effect. The relevant article has been published in the Neural Regeneration Research (Vol. 9, No. 6, 2014).

The static nerve arranged regularly in the adhesive group observed by transmission electron microscopy (× 1,000).

Article: " Sciatic nerve repair using adhesive bonding and a modifed conduit," by Xiangdang Liang1, Hongfei Cai1, Yongyu Hao2, Geng Sun3, Yaoyao Song1, Wen Chen1 (1 Department of Orthopedics, General Hospital of Chinese PLA, Beijing, China; 2 Wei Zikeng Clinic of General Armament Department of Chinese PLA, Beijing, China; 3 Department of Orthopedics, 252 Hospital of Chinese PLA, Hebei Province, China)

Liang XD, Cai HF, Hao YY, Sun G, Song YY, Chen W. Sciatic nerve repair using adhesive bonding and a modified conduit. Neural Regen Res.

2014;9(6):594-601.